A Guide to 2nd Line Treatments and New Treatments on the Horizon

Hear from Dr. Susan Shenoi on how to unlock the knowledge you need to make informed decisions about 2nd line treatments and the promising new therapies on the horizon. In this town hall, you will understand the next steps in your treatment journey, and be empowered with the latest insights and options.


Dr. Shenoi’s town hall details:

A basic understanding of JM – Dr. Shenoi describes myositis as a pizza topping analogy. Myositis is the base and the autoantibodies are the toppings. This analogy paints the picture of the many different disease courses in juvenile dermatomyositis and how unique they are.

Immune System Pathways – Dr. Shenoi provides a graphic of the immune system’s makeup that is really interesting and shows how different drugs target different pathways.

Combination Therapy – Since there is not an exact science as to which immune pathway to target, Dr. Shenoi and other JM experts believe that “combination therapy” is ideal for treatment. For example, abatacept might target the T-cell path, while Rituximab targets the B-cells. The combination of drugs targeting multiple immune system paths creates better outcomes.

Who should know these options – The primary goal of adding 2nd or 3rd line treatment options is to reduce and eliminate prednisone (steroids) as it comes with long term side effects. These options will hopeful allow for more control of the juvenile myositis without steroids and optimize a patients quality of life!

    Balancing Work and Caregiving: Strategies for Working Parents of Children with Juvenile Myositis

    Balancing Work and Caregiving: Strategies for Working Parents of Children with Juvenile Myositis

    Balancing the demands of a career with the responsibilities of caregiving is a challenging task for any parent. For those with a child diagnosed with juvenile myositis (JM), a rare autoimmune disease affecting children, the challenge is heightened. Juggling work commitments while providing the necessary care and support for a child with JM can be taxing. In this article, we hope to provide you with a few effective strategies and insights to help working parents navigate this delicate balance.

    Emma's Story of Hope, Giving Tuesday 2024

    Emma’s Story of Hope – A Tale of Life-Changing Care

    At 12 years old, Emma’s world was turned upside down. An energetic cheerleader who loved spending time with her friends, she suddenly found herself constantly fatigued, her muscles weak and aching. What began as mild discomfort quickly escalated into something far more serious.

    May 2025 Town Hall, Dr. Ardalan

    Tapering Medication

    Cure JM hosted a special Town Hall featuring Dr. Kaveh Ardalan, Co-Director of the Duke Children’s Myositis Center, a Cure JM Center of Excellence. The

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