June 2026 Town Hall – CAR-T

June 2026 Town Hall

On June 16, Cure JM’s Shannon Malloy sat down with Tania Gonzalez Rivera, VP of Medical Affairs, and Courtney Little, Senior Director and Clinical Scientist at Cabaletta Bio, for a conversation about the RESET‑Myositis CAR‑T trial and new research updates presented at the European rheumatology conference. Dr. Holly Wobma, pediatric rheumatologist at Boston Children’s Hospital and Harvard Medical School, also joined the discussion to help families understand how CAR‑T therapy works and what the science means for Juvenile Myositis patients specifically.

The conversation covered:

• how CAR‑T therapy works

• what treatment and enrollment look like

• early clinical results and safety observations

• what researchers are learning so far

• how families can learn whether their child, teen, or young adult may be eligible at a site near them

Dr. Younghun Han: Shared DNA Clues Point to Faster Treatments for Juvenile Myositis.

Shared DNA Clues Point to Faster Treatments for Juvenile Myositis

In a study funded by the Cure JM Foundation and spearheaded by Dr. Younghun Han of the Baylor College of Medicine, scientists compared the DNA of more than three thousand people living with myositis to nearly twelve thousand healthy volunteers and found something striking. The major forms of myositis share much of the same genetic wiring.

Understanding Second line treatments and side effects

Understanding Second-Line Treatments and Side Effects

Second-line treatments refer to options beyond steroids and methotrexate. They are designed to manage JM while reducing reliance on those medications. We understand that adding new treatments to your child’s regimen can be intimidating. However, rest assured that your doctor has carefully considered the benefits and risks of each option to design the best treatment plan for your family.

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Cure JM supports families, patients, and the juvenile myositis research community.

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