A Guide to 2nd Line Treatments and New Treatments on the Horizon

Hear from Dr. Susan Shenoi on how to unlock the knowledge you need to make informed decisions about 2nd line treatments and the promising new therapies on the horizon. In this town hall, you will understand the next steps in your treatment journey, and be empowered with the latest insights and options.


Dr. Shenoi’s town hall details:

A basic understanding of JM – Dr. Shenoi describes myositis as a pizza topping analogy. Myositis is the base and the autoantibodies are the toppings. This analogy paints the picture of the many different disease courses in juvenile dermatomyositis and how unique they are.

Immune System Pathways – Dr. Shenoi provides a graphic of the immune system’s makeup that is really interesting and shows how different drugs target different pathways.

Combination Therapy – Since there is not an exact science as to which immune pathway to target, Dr. Shenoi and other JM experts believe that “combination therapy” is ideal for treatment. For example, abatacept might target the T-cell path, while Rituximab targets the B-cells. The combination of drugs targeting multiple immune system paths creates better outcomes.

Who should know these options – The primary goal of adding 2nd or 3rd line treatment options is to reduce and eliminate prednisone (steroids) as it comes with long term side effects. These options will hopeful allow for more control of the juvenile myositis without steroids and optimize a patients quality of life!

    Ronda Thorington, April Town Hall Web Size, Updated for Resources

    Resilient Parenting

    Parenting a child with a rare disease comes with unique challenges—but you don’t have to navigate them alone. Join us for a powerful and practical

    Why I Walk- Sammie Fish

    Why I Walk: Steps Toward a Cure with Sammie Fish

    Sammie Fish was 14 when juvenile dermatomyositis (JDM, a rare form of juvenile myositis (JM) changed her life in 2017. A doctor’s warning that she might never reach remission, tied to a lifetime of medication, shook her world. But Sammie, now 21, didn’t back down. Today, she’s a college grad, a new teacher in her dream job, and Co-Chair of Cure JM’s Ohio Chapter alongside her mom. She walks for herself, for kids like her, and for a cure. That’s why hundreds of Cure JM families and friends across the nation join Walk Strong, because every step pushes us toward a JM-free future

    Research Update: misbehaving Mitochondria Linked to Juvenile Dermatomyositis. Dr. Christian Lood

    Breakthrough Discovery: Misbehaving Mitochondria Linked to Juvenile Dermatomyositis

    The generous support of our community has been instrumental in funding groundbreaking research this year, led by Dr. Christian Lood at the University of Washington and Cure JM’s Center of Excellence at Seattle Children’s Hospital. Dr. Lood’s team has identified calcified mitochondria in the muscle tissue of JDM patients with calcinosis – a finding that sheds new light on understanding JDM

    Join Cure JM

    Membership is free and we’ll connect you with a network of support, encouragement, and resources.

    Cure JM supports families, patients, and the juvenile myositis research community.

    Interested in DIY fundraising but need help?

    We’re here to help!

    To have your fundraiser matched, add “DIY Match” in the memo of your online gift or check.